5000 Plus MCQs for Lab Technician and Technologists are designed to test the knowledge and proficiency of laboratory professionals who work in the field of clinical laboratory science. These questions cover a wide range of topics related to laboratory science, including anatomy, physiology, microbiology, chemistry, and hematology.
1351 to 1400 MCQs for Lab Technician and Technologist Exam Preparation
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Questions 1351 to 1400
Which of the following electrolytes is the chief plasma cation whose main function is maintaining osmotic pressure?
- a) Chloride
- b) Calcium
- c) Potassium
- d) Sodium
The solute that contributes the most to the total serum osmolality is:
- a) Glucose
- b) Sodium
- c) Chloride
- d) Urea
Which of the following is true about direct ion selective electrode is falsely decreased by:
- a) Whole blood specimens are acceptable
- b) Elevated lipids cause falsely decreased results
- c) Elevated proteins cause falsely decreased results
- d) Elevated platelets cause falsely increased results
Sodium determination by indirect ion selective electrode is falsely decreased by:
- a) Elevated chloride levels
- b) Elevated lipid levels
- c) Decreased protein levels
- d) Decreased albumin levels
Which percentage of total serum calcium is nondiffusible protein bound?
- a) 80%-90%
- b) 51%-60%
- c) 40%-50%
- d) 10%-30%
Calcium concentration in the serum is regulated by:
- a) Insulin
- b) Parathyroid hormone
- c) Thyroxine
- d) Vitamin C
The regulation of calcium and phosphorus metabolism is accomplished by which of the following glands?
- a) Thyroid
- b) Parathyroid
- c) Adrenal glands
- d) Pituitary
A hospitalized patient is experiencing increased neuromuscular irritability (tetany). Which of the following tests should be ordered immediately?
- a) Calcium
- b) Phosphate
- c) BUN
- d) Glucose
Which of the following is most likely to be ordered in addition to serum calcium to determine the cause of tetany?
- a) Magnesium
- b) Phosphate
- c) Sodium
- d) Vitamin
A reciprocal relationship exists between:
- a) Sodium and potassium
- b) Calcium and phosphate
- c) Chloride and CO2
- d) Calcium and magnesium
Fasting serum phosphate concentration is controlled primarily by the:
- a) Pancreas
- b) Skeleton
- c) Parathyroid glands
- d) Small intestine
A low concentration of serum phosphorus is commonly found in:
- a) Patients who are receiving carbohydrate hyperalimentation
- b) Chronic renal disease
- c) Hypoparathyroidism
- d) Patients with pituitary tumors
The primary function of serum albumin in the peripheral blood is to:
- a) Maintain colloidal osmotic pressure
- b) Increase antibody production
- c) Increase fibrinogen formation
- d) Maintain blood viscosity
The first step in analyzing a 24-hour urine specimen for quantitative urine protein is:
- a) Subculture the urine for bacteria
- b) Add the appropriate preservative
- c) Screen for albumin using a dipstick
- d) Measure the total volume
Total iron-binding capacity measures the serum iron transporting capacity of:
- a) Hemoglobin
- b) Cerruloplasmin
- c) Transferrin
- d) Fetrritin
The first step in the quantitation of serum iron is:
- a) Direct reaction with appropriate chromagen
- b) Iron saturation of transferrin
- c) Free iron precipitation
- d) Separation of iron from transferrin
A serum sample demonstrates an elevated result when tested with the Jaffe reaction. This indicates:
- a) Prolonged hypothermia
- b) Renal functional impairment
- c) Pregnancy
- d) Arrhythmia
Creatinine clearance is used to estimate the:
- a) Tubular secretion of creatinine
- b) Glomerular secretion of creatinine
- c) Renal glomerular and tubular mass
- d) Glomerular filtration rate
90% of the copper present in the blood is bound to:
- a) Transferrin
- b) Ceruloplasmin
- c) Albumin
- d) Cryoglobulin
Hemoglobin S can be separated from hemoglobin D by:
- a) Electrophoresis on a different medium and acidic pH
- b) Hemoglobin A2 quantitation
- c) Electrophoresis at higher voltage
- d) Kleihauer-Betke acid elution
On electrophoresis at alkaline pH, which of the following is the slowest migrating hemoglobin?
- a) Hgb A
- b) Hgb S
- c) Hgb C
- d) Hgb F
Urobilinogen is formed in the:
- a) Kidney
- b) Spleen
- c) Liver
- d) Intestine
Kernicterus is an abnormal accumulation of bilirubin in:
- a) Heart tissue
- b) Brain tissue
- c) Liver tissue
- d) Kidney tissue
A stool specimen that appears black and tarry should be tested for the presence of:
- a) Occult blood
- b) Fecal fat
- c) Trypsin
- d) Excess mucus
The most specific enzyme test for acute pancreatitis is:
- a) Acid phosphatase
- b) Trypsin
- c) Amylase
- d) Lipase
Which of the following enzymes are used in the diagnosis of acute pancreatitis?
- a) Amylase (AMS) and lipase (LPS)
- b) Aspartate aminotransferase (AST) and alanine aminotransferase (ALT)
- c) 5′ -nucleotidase (5’N) and gamma-glutamyl transferase (GGT)
- d) Aspartate aminotransferase (AST) and lactate dehydrogenase (LD)
Which of the following enzymes catalyzes the conversion of starch to glucose and maltose?
- a) Malate dehydrogenase (MD)
- b) Amylase (AMS)
- c) Creatine kinase (CK)
- d) Isocitric dehydrogenase (ICD)
Aspartate amino transferase (AST) is characteristically elevated in diseases of the:
- a) Liver
- b) Kidney
- c) Intestine
- d) Pancreas
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are both elevated in which of the following diseases?
- a) Muscular dystrophy
- b) Viral hepatitis
- c) Pulmonary emboli
- d) Infectious mononucleosis
The greatest activities of serum AST and ALT are seen in which of the following?
- a) Acute viral hepatitis
- b) Primary biliary cirrhosis
- c) Metastatic hepatic cirrhosis
- d) Alcoholic cirrhosis
Which of the following clinical disorders is associated with the greatest elevation of lactate dehydrogenase isoenzyme 1?
- a) Pneumonia
- b) Glomerulonephritis
- c) Pancreatitis
- d) Pernicious anemia
The enzyme present in almost all tissues that may be separated by electrophoresis into 5 components is:
- a) Lipase
- b) Transaminase
- c) Creatine kinase
- d) Lactate dehydrogenase
A common cause of falsely increased LD1 fraction of lactic dehydrogenase is:
- a) Specimen hemolysis
- b) Liver disease
- c) Congestive heart failure
- d) Drug toxicity
The presence of which of the following isoenzymes indicates acute myocardial damage?
- a) CKMM
- b) CKMB
- c) CKBB
- d) None
In which of the following conditions would a normal level of creatine kinase be found?
- a) Acute myocardial infarct
- b) Hepatitis
- c) Progressive muscular dystrophy
- d) Intramuscular injection
Of the following diseases, the one most often associated with elevations of lactate dehydrogenase isoenzymes 4 and 5 on electrophoresis is:
- a) Liver disease
- b) Hemolytic anemia
- c) Myocardial infarction
- d) Pulmonary edema
When myocardial infarction occurs, the first enzyme to become elevated is:
- a) CK
- b) LD
- c) AST
- d) ALT
In the immunoinhibition phase of the CKMB procedure:
- a) M subunit is inactivated
- b) B subunit is inactivated
- c) MB is inactivated
- d) BB is inactivated
The presence of increased CKMB activity on a CK electrophoresis pattern is most likely found in a patient suffering from:
- a) Acute muscular stress following strenuous exercise
- b) Malignant liver disease
- c) Myocardial infarction
- d) Severe head injury
Increased serum lactic dehydrogenase activity due to elevation of fast fraction (1 and 2) on electrophoretic separation is caused by:
- a) Nephrotic syndrome
- b) Hemolytic anemia
- c) Pancreatitis
- d) Hepatic damage
Regan isoenzyme has the same properties as alkaline phosphatase that originates in the:
- a) Skeleton
- b) Kidney
- c) Intestine
- d) Placenta
The most heat labile fraction of alkaline phosphatase is obtained from:
- a) Liver
- b) Bone
- c) Intestine
- d) Placenta
The most sensitive enzymatic indicator for liver damage from ethanol intake is:
- a) Alanine aminotransferase (ALT)
- b) Aspartate aminotransferase (AST)
- c) Gamma-glutamyl transferase (GGT)
- d) Alkaline phosphatase
Isoenzyme assays are performed to improve:
- a) Precision
- b) Accuracy
- c) Sensitivity
- d) Specificity
The protein portion of an enzyme complex is called the:
- a) Apoenzyme
- b) Coenzyme
- c) Holoenzyme
- d) Proenzyme
Which of the following chemical determinations may be of help in establishing the presence of seminal fluid?
- a) Lactic dehydrogenase (LD)
- b) Isocitrate dehydrogenase (ICD)
- c) Acid phosphatase
- d) Alkaline phosphatase
Chylomicrons are present in which of the following dyslipidemias?
- a) Familial hypercholesterolemia
- b) Hypertriglyceridemia
- c) Deficiency in lipoprotein lipase activity
- d) Familial hypoalphalipoproteinemia
Turbidity in serum suggests elevation of:
- a) Cholesterol
- b) Total protein
- c) Chylomicrons
- d) Albumin
TSH is produced by the:
- a) Hypothalamus
- b) Pituitary gland
- c) Adrenal cortex
- d) Thyroid
The majority of thyroxine (T4) is converted into the more biologically active hormone:
- a) Thyroglobulin
- b) Thyroid-stimulating hormone (TSH)
- c) Triiodothyronine
- d) Thyrotropin-releasing hormone
Answer Key Summary
The questions are typically designed to assess the technical skills and knowledge required for the laboratory profession, including the ability to analyze laboratory test results, perform laboratory procedures, and maintain laboratory equipment.
To prepare for these MCQs, candidates should have a thorough understanding of the key concepts and principles of laboratory science. They should also be familiar with common laboratory equipment and procedures, as well as laboratory safety protocols.
Candidates may also benefit from studying specific laboratory science textbooks or taking online courses that cover the material tested in the MCQs. Additionally, practicing sample MCQs and reviewing the answers can help candidates identify areas where they may need to improve their knowledge or skills.
Overall, the MCQs for lab technologists are designed to be challenging and comprehensive, requiring candidates to demonstrate a high level of proficiency in the field of laboratory science.
