5000 Plus MCQs for Lab Technician and Technologists are designed to test the knowledge and proficiency of laboratory professionals who work in the field of clinical laboratory science. These questions cover a wide range of topics related to laboratory science, including anatomy, physiology, microbiology, chemistry, and hematology.
501 to 550 MCQs for Lab Technician and Technologist Exam Preparation
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Questions 501 to 550
Thiamine is vitamin
- a) B1
- b) B2
- c) B6
- d) B12
The iron stored in intestinal mucosal cells is complexed to
- a) Ferritin
- b) Intrinsic factor
- c) Oprelvekin
- d) Transcobalamin II
- e) Transferrin
Which of the following is most likely to be required by a 5-year-old boy with chronic renal insufficiency?
- a) Erythropoietin
- b) G-CSF
- c) Interleukin
- d) Stem cell factor
- e) Thrombopoietin
In adults, approximately ______ mg of thiamine per day is completely degraded by the tissue
- a) 0.01
- b) 0.1
- c) 1.0
- d) 10.0
The drug of choice for the management of osteoporosis caused by high-dose use of glucocorticoids is
- a) Alendronate
- b) Calcitonin
- c) Mestranol
- d) Oxandrolone
- e) Vitamin D
Which of the following drugs is correctly associated with its clinical application?
- a) Erythropoietin : Macrocytic anemia
- b) Filgrastim : Thrombocytopenia due to myelocytic leukemia
- c) Iron dextran : Severe macrocytic anemia
- d) Ferrous sulfate : Microcytic anemia of pregnancy
- e) Folic acid : Hemochromatosis
Conversion of methionine to cysteine depends on vitamin
- a) B1
- b) B2
- c) B6
- d) B12
Avidin, a protein found in egg white, is an antagonist of
- a) Biotin
- b) Pantothenic acid
- c) Choline
- d) Pyridoxal
All of the following are important functions of magnesium (Mg) except
- a) Nerve conduction
- b) Phospholipid synthesis
- c) Muscle contractility
- d) Carbohydrate, fat, and electrolyte metabolism
Factors likely to cause an increase in the blood urea nitrogen (BUN) level include
- a) Intramuscular (IM) injection of diazepam (Valium)
- b) Severe liver disease
- c) Chronic kidney disease
Physiologically carnitine plays following role
- a) Important for oxidation of fatty acids
- b) Decreases aerobic metabolism of carbohydrates
- c) Decreases rate of oxidative phosphorylation
- d) All (a, b, & c) Options
Patients receiving iron therapy should be warned about
- a) Dizziness
- b) Ringing in the ears
- c) Danger of sunlight
- d) Blackening of the stool
- e) Paresthesia
Therapeutically vitamin B1 has been employed most successfully in the treatment of
- a) Microcytic anemia
- b) Pellagra
- c) Scurvy
- d) Beriberi
- e) Macrocytic anemia
Magnesium ion is necessary in
- a) Stimulating enzyme systems
- b) Muscular contraction
- c) Nerve conduction
- d) All “a” & “b” options
- e) None of “a” & “b” Options
The following derivatives of retinal shows the greatest biological potency than others
- a) 9-Cis-retinoic acid
- b) All-trans-retinoic acid
- c) All-trans-retinol
- d) 11-Cis-retinal
The drug used for controlling tetany is
- a) Intravenous diazepam
- b) Intramuscular vitamin D
- c) Intravenous calcium gluconate
- d) Intravenous calcitonin
Absorption of oral iron preparations can be facilitated by coadministering
- a) Antacids
- b) Tetracyclines
- c) Phosphates
- d) Ascorbic acid
The gut controls the entry of ingested iron in the body by
- a) Regulating the availability of apoferritin which acts as the carrier of iron across the mucosal cell
- b) Regulating the turnover of apoferritin-ferritin interconversion in the mucosal cell
- c) Complexing excess iron to form ferritin which remains stored in the mucosal cell and is shed off
- d) Regulating the number of transferrin receptors on the mucosal cell
The percentage of elemental iron in hydrated ferrous sulfate is
- a) 5%
- b) 10%
- c) 20%
- d) 33%
In isolated fibroblast or epithelial cells, retinoids enhance the synthesis of following protein
- a) Fibronectin
- b) Collagenase
- c) Certain species of keratin
- d) All (a, b, & c) Options
The side effect which primarily limits acceptability of oral iron therapy is
- a) Epigastric pain and bowel upset
- b) Black stools
- c) Staining of teeth
- d) Metallic taste
Iron sorbitol-citric acid differs from iron dextran in that
- a) It cannot be injected i.v.
- b) It is not excreted in urine
- c) It is not bound to transferrin in plasma
- d) It produces fewer side effects
Which of the following is true about iron therapy?
- a) Haemoglobin response to intramuscular iron is faster than with oral iron therapy
- b) Iron must be given orally except in pernicious anaemia
- c) Prophylactic iron therapy must be given during pregnancy
- d) Infants on breast feeding do not require medicinal iron
Concentrations of retinal in plasma in excess of _____ µg/dl usually are diagnostic of hypervitaminosis A
- a) 10
- b) 50
- c) 100
- d) 200
Megaloblastic anaemia occurs in
- a) Vitamin B12 but not folic acid deficiency
- b) Folic acid but not Vitamin B12 deficiency
- c) Either Vitamin B12 or folic acid deficiency
- d) Only combined Vitamin B12 + folic acid deficiency
The daily dietary requirement of Vitamin B12 by an adult is
- a) 1-3 µg
- b) 50-100 µg
- c) 0.1-0.5 µg
- d) 5-10 µg
Which of the following factor(s) is/are required for the absorption of Vitamin B12 ingested in physiological amounts?
- a) Gastric acid
- b) Gastric intrinsic factor
- c) Transcobalamine
- d) Both (a) and (b)
Hydroxocobalamine differs from cyanocobalamine in that
- a) It is more protein bound and better retained
- b) It is beneficial in tobacco amblyopia
- c) It benefits haematological but not neurological manifestations of Vit B12 deficiency
- d) Both (a) and (b)
Megaloblastic anemia is caused by deficiency of
- a) Iron
- b) Vitamin B12
- c) Vitamin C
- d) All (a, b, & c) Options
Vitamin B12 is a required co-factor for the following reaction
- a) Conversion of methylmalonyl-CoA to succinyl-CoA
- b) Conversion of 5-CH3-H4-folate to H4-folate
- c) Conversion of homocysteine to methionine
- d) All (a, b, & c) Options
Vitamin K is indicated for the treatment of bleeding occurring in patients
- a) Being treated with heparin
- b) Being treated with streptokinase
- c) Of obstructive jaundice
- d) Of peptic ulcer
Menadione (Vitamin K3)
- a) Can cause hemolysis in patients with G-6-PD deficiency
- b) Is given in large doses in patients with severe liver disease
- c) Is useful to prevent haemorrhagic disease of the newborn
- d) Is the preparation of choice to antagonize the effect of warfarin overdose
Vitamin K promotes the hepatic biosynthesis of following blood clotting factor
- a) Factor I
- b) Factor II
- c) Factor VIII
- d) All (a, b, & c) Options
Folinic acid is principally used
- a) In pernicious anaemia
- b) In megaloblastic anaemia secondary to Vitamin B12
- c) Along with methotrexate therapy
- d) In treatment of folic acid deficiency
Penicillamine
- a) Is effective orally
- b) Can cause anaphylactic reactions in patients allergic to penicillin
- c) Is safe in pregnancy
- d) Is not effective in lead poisoning
Succimer
- a) Can significantly mobilize essential metals
- b) Produces less toxicity than Dimercaprol
- c) Is ineffective orally
- d) Is contraindicated in children
Causes spurious decrease in MCV
- a) Cryofibrinogen
- b) Hyperglycemia
- c) Autoagglutination
- d) High WBC count
- e) Reduced red cell deformability
When the entire CBC is suppressed due to either anemia, infection, or hemorrhage is called?
- a) Erythroplasia
- b) Thrombocytopenia
- c) Pancytopenia
- d) Leukopenia
Total RBC count for Women is?
- a) 4.4 – 6
- b) 4.2 – 5
- c) 4.0 – 5.0
- d) 4.2 – 5.2
Total RBC for men?
- a) 4.0 – 5.0
- b) 4.6 – 6.0
- c) 4.2 – 6.5
- d) 4.0 – 6.0
What is the major metabolically available storage form of iron in the body?
- a) Hemosiderin
- b) Ferritin
- c) Transferrin
- d) Hemoglobin
The best source of active bone marrow from a 20-year old would be:
- a) Iliac Crest (hip)
- b) Femur (thigh)
- c) Distal radius (forearm)
- d) Tibia (shin)
Laboratory Studies: Red Cell Indices: Determination of relative size of RBC. 82-98 fl
- a) MCH
- b) MCV
- c) MCHC
- d) HCT
Laboratory Studies: Red Cell Indices: Measurement of average weight of Hb/RBC. 27-33 pg
- a) HCT
- b) MCV
- c) MCH
- d) MCHC
Laboratory Studies: Red Cell Indices: Evaluation of RBC saturation with Hb. 32-36%
- a) HCT
- b) MCV
- c) MCH
- d) MCHC
There are 3 main classifications of anemia. Which of the following is NOT one of them?
- a) In adequate production of Hb
- b) Decreased RBC production
- c) Increased Erythrocyte destruction
- d) Blood loss
Vitamin B12 and folic acid have similar adverse effects, but what separates one from the other?
- a) Glossitis
- b) No neurological symptoms in folic acid
- c) Muscle wasting
- d) Dizziness
Folic acid therapy can cause sickle cell anemia
- a) True
- b) False
- c) Equal
- d) All (a, b, & c) Options
Both vitamin B12 AND iron have drug interactions with which of the following drugs?
- a) PPI, H2 blockers
- b) Methyldopa
- c) Metformin
Hydroxyurea increases hemoglobin production and decreases reticulocyte cells.
- a) True
- b) False
Answer Key Summary
The questions are typically designed to assess the technical skills and knowledge required for the laboratory profession, including the ability to analyze laboratory test results, perform laboratory procedures, and maintain laboratory equipment.
To prepare for these MCQs, candidates should have a thorough understanding of the key concepts and principles of laboratory science. They should also be familiar with common laboratory equipment and procedures, as well as laboratory safety protocols.
Candidates may also benefit from studying specific laboratory science textbooks or taking online courses that cover the material tested in the MCQs. Additionally, practicing sample MCQs and reviewing the answers can help candidates identify areas where they may need to improve their knowledge or skills.
Overall, the MCQs for lab technologists are designed to be challenging and comprehensive, requiring candidates to demonstrate a high level of proficiency in the field of laboratory science.
