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Paracetamol, also known as acetaminophen, is a medicine used to treat pain and fever. It is usually used for mild to moderate pain relief. The evidence is conflicting about its use to relieve fever in children. It is often sold in combination with other medications, as in many cold medications.

Also Known asAcetaminophen, Tylenol, Paracetamol, N-acetyl-p-aminophenol
Test PurposeTo determine if an overdose has occurred and if an antidote is required
To determine risk of liver damage and to help monitor the outcome of antidote treatment
Test PreparationsNo need any preparations
Test ComponentsAcetaminophen
Specimen2 ML (1.5 ML Min.) Serum From 1 SST. Ship Refrigerated Or Frozen.
Stability Room2 Hrs
Stability Refrigerated24 Hrs
Stability Frozen1 Week
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  • Most people think of Tylenol as the safest pain reliever.
  • It is used for headache, joint pain (arthritis), and fever.
  • But its excessive use or overdose can lead to poisoning and side effects.
  • In healthy people, the overdose is greater than 150 mg / kg of body weight.
  • Tylenol basically causes liver damage.
  • Its poisoning effects are phased.

Normal Values:

The toxic level is> 5.0 micrograms / ml when the patient is at high risk.

Phase 1

There will be mild nausea and abdominal discomfort.

This phase is self-limited and the patient may feel better after a few hours.

Phase 2

There can be side effects after 24 hours and the patient can develop liver damage.

There is progressive necrosis or injury of liver cells.

Phase 3:

Ultimately, there will be fulminant hepatitis leading to liver failure.

Phase 4:

This is the healing stage and resolution begins and can lead to a full recovery.
Other possibilities are that there is no recovery and the patient may need a liver transplant.
The last possibility is death.

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