5000 Plus MCQs for Lab Technician and Technologists are designed to test the knowledge and proficiency of laboratory professionals who work in the field of clinical laboratory science. These questions cover a wide range of topics related to laboratory science, including anatomy, physiology, microbiology, chemistry, and hematology.
551 to 600 MCQs for Lab Technician and Technologist Exam Preparation
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Questions 551 to 600
Hydroxyurea:
- a) Decreases nitric oxide
- b) Increases neutrophil and monocytes
- c) Inhibits DNA synthesis by acting as a ribonucleotide reductase inhibitor
- d) None of “a”, “b” & “c” Options
Hydroxyurea increases the serum uric acid levels.
- a) True
- b) False
Decitabine increases the fetal hemoglobin production by inducing methylation of DNA and thus prevents the switch from gamma to beta-globin production.
- a) True
- b) False
Hypocupremia is seen in
- a) Osteoporosis, nephrotic disease
- b) Sprue, celiac disease
- c) Cardiovascular disease, colon cancer
- d) All of “a”, “b” & “c” Options
Wilsons disease can cause liver problems
- a) True
- b) False
What are the treatment options for Wilson’s disease?
- a) Penicillamine
- b) Trientine
- c) Potassium disulfide
- d) Zinc
- e) All of “a”, “b”, “c” & “d” Options
Aplasia can occur because of riboflavin deficiency?
- a) True
- b) False
Angular stomatitis/cheilosis is a symptom of vitamin B12 deficiency?
- a) True
- b) False
Antimalarial drugs and high dose birth control will increase riboflavin.
- a) True
- b) False
Which test can be used to detect hemolytic anemia?
- a) Coombs test
- b) Genetic testing
- c) Peripheral blood smear (PBS)
- d) Schilling test
Which anemia is classified as not being able to use iron properly to synthesize hemoglobin because of an inherited cause?
- a) Iron deficiency anemia
- b) Hypochromic anemia
- c) Aplastic anemia
Aplastic anemia can be induced by drugs such as Lithium, acetazolamide, and aspirin.
- a) True
- b) False
This fatal disorder results from clot/thrombus formation in the blood circulation.
- a) Thromboembolism
- b) DVT
- c) PAD
- d) Pulmonary embolism
- e) All of “a”, “b”, “c” & “d” Options
Homan’s sign is classified as pain behind the knee.
- a) True
- b) False
Patients that are sensitive to aspirin can take:
- a) Sulfinpyrazone
- b) Clopidogrel
- c) Ticlopidine
- d) All of “a”, “b” & “c” Options
What is the life span of RBC?
- a) 200
- b) 120
- c) 100
- d) 80
This drug can potentiate the effect of prostacyclins to antagonize platelet stickiness and therefore decreases platelet adhesion to thrombogenic surfaces.
- a) Sulfinpyrazone
- b) Dipyridamole
- c) Ticlopidine
Which drug can be given as a prophylaxis for cardiovascular effects?
- a) Ticlopidine
- b) Clopidogrel
- c) Dipyridamole
Which drug can increase intracellular levels of cAMP by inhibiting cyclic nucleotide phosphodiesterase?
- a) Sildenafil
- b) Ticlopidine
- c) Clopidogrel
- d) Dipyridamole
Warfarin should be used with caution in the following:
- a) Alcoholic liver disease
- b) Gastrointestinal bleeding
- c) Recent neurosurgery
- d) Liver impairment
Isozymes of 2C can greatly affect warfarin.
- a) True
- b) False
Absolute lymphocytosis (>5000/mm³) without adenopathy, hepatosplenomegaly, anemia, or thrombocytopenia is what stage in CLL prognosis according to Rai Staging System?
- a) Stage 0
- b) Stage I
- c) Stage II
- d) Stage III
- e) Stage IV
Conventional treatment is ______ for Rai stage II.
- a) Antibiotics
- b) Chemotherapy
- c) Antivirals
- d) Rest
In patients with low numbers of neoplastic cells, sometimes due to treatment, PCR to amplify DNA can improve sensitivity, and detect signs of relapse.
- a) True
- b) False
Chronic lymphocytic leukemia is the most common leukemia in what kind of people?
- a) Young adults
- b) Older adults
Absolute lymphocytosis and thrombocytopenia (<100,000/mm³) with or without lymphadenopathy, hepatomegaly, splenomegaly, or anemia is what stage in CLL prognosis according to Rai Staging System?
- a) Stage 0
- b) Stage I
- c) Stage II
- d) Stage III
- e) Stage IV
Chronic Lymphocytic Leukemia is characterized by peripheral blood and bone marrow _____.
- a) Lymphocytopenia
- b) Lymphocytosis
Chronic Lymphocytic Leukemia is characterized by gradual accumulation of small mature ______ cells.
- a) T
- b) B
- c) NK
Which of the following is the most mature normoblast?
- a) Orthochromic Normoblast
- b) Basophilic Normoblast
- c) Pronormoblast
- d) Polychromatic Normoblast
Absolute lymphocytosis with either hepatomegaly or splenomegaly with or without lymphadenopathy is what stage in CLL prognosis according to Rai Staging System?
- a) Stage 0
- b) Stage I
- c) Stage II
- d) Stage III
- e) Stage IV
Absolute lymphocytosis without lymphadenopathy, without hepatosplenomegaly, anemia, or thrombocytopenia is what stage in CLL prognosis according to Rai Staging System?
- a) Stage 0
- b) Stage I
- c) Stage II
- d) Stage III
- e) Stage IV
In Chronic Lymphocytic Leukemia, the lymphocyte appearance: small or slightly larger than normal, hyper-condensed (almost ________ appearing) nuclear chromatin pattern. Bare nuclei called “smudge cells” are common.
- a) soccer-ball
- b) basketball
- c) football
- d) tennis-ball
Which of the following forms of Hb molecule has the lowest affinity for oxygen?
- a) Tense
- b) Relaxed
- c) Arterial
- d) Venous
What is the recommended cleaner for removing all oil from objective lens?
- a) 70% alcohol or lens cleaner
- b) Xylene
- c) Water
- d) Benzene
Intravascular hemolysis is the result of trauma to RBCs while in the circulation
- a) True
- b) False
A 1:20 dilution was made in a Unopette, with glacial acetic acid as the diluent. The four corner squares on BOTH sides of the hemacytometer are counted for a total of 100 cells. What is the total WBC (x109/L)?
- a) 0.25
- b) 2.5
- c) 5
- d) 10
The shape of a cell is maintained by which of the following?
- a) Microtubules
- b) Spindle Fibers
- c) Ribosomes
- d) Centrioles
At which month of fetal development does the bone marrow become the primary site of hematopoiesis?
- a) 2nd
- b) 5th
- c) End of 6th month
- d) End of 7th month
Which types of cells develop from yolk sac (Mesoblastic phase)?
- a) Hb F, Hg A2, and Hg A
- b) Gower 1 and Gower 2 Hgb
- c) Portland Hgb
- d) Only Erythroblasts
Normal Adult Hb A contains the following polypeptide chains:
- a) alpha and beta
- b) alpha and epsilon
- c) alpha and delta
- d) alpha and brotherton
Allergic reactions are frequently associated with an increase in the presence of:
- a) Lymphocytes
- b) Neutrophils
- c) Monocytes
- d) Eosinophils
Lipid exchange between the RBC membrane and the plasma occurs:
- a) To replace lost lipids in the membrane
- b) To provide a mechanism for excretion of lipid-soluble RBC waste products
- c) To ensure symmetry between the composition of the interior and exterior lipid layers
- d) To provide lipid-soluble nutrients to the RBC
After the microscope has been adjusted for Kohler illumination, light intensity should never be regulated by using the…
- a) Rheostat
- b) Neutral density filter
- c) Kohler magnifier
- d) Condenser
Which of the following types of microscopy is valuable in the identification of crystals that are able to rotate light?
- a) Compound brightfield
- b) Darkfield
- c) Polarizing
- d) Phase-contrast
During the Medullary Phase of hematopoietic development, which bone is the first to show hematopoietic activity?
- a) Femur
- b) Iliac Crest
- c) Skull
- d) Clavicle
Given the following values, calculate the RPI: Observed reticulocyte count – 6%, Hct – 30%
- a) 2
- b) 3
- c) 4
- d) 5
The lipids of the RBC membrane are arranged:
- a) In chains beneath a protein exoskeleton
- b) So that the hydrophobic portions are facing the plasma
- c) In a hexagonal lattice
- d) In two layers that are not symmetric in composition
The hexose monophosphate pathway activity increases the RBC source of:
- a) Glucose and lactic acid
- b) 2,3-BPG and methemoglobin
- c) NADPH and reduced glutathione
- d) ATP and other purine metabolites
Which single feature of normal RBCs is most responsible for limiting their life span?
- a) Loss of mitochondria
- b) Increased flexibility of the cell membrane
- c) Reduction of Hb iron
- d) Loss of nucleus
In the Iron cycle, the transferrin receptor carries:
- a) Iron out of duodenal cells from the intestinal lumen
- b) Iron out of duodenal cells into the plasma
- c) Transferrin-bound iron in the plasma
- d) Transferrin-bound iron into erythrocytes
Answer Key Summary
The questions are typically designed to assess the technical skills and knowledge required for the laboratory profession, including the ability to analyze laboratory test results, perform laboratory procedures, and maintain laboratory equipment.
To prepare for these MCQs, candidates should have a thorough understanding of the key concepts and principles of laboratory science. They should also be familiar with common laboratory equipment and procedures, as well as laboratory safety protocols.
Candidates may also benefit from studying specific laboratory science textbooks or taking online courses that cover the material tested in the MCQs. Additionally, practicing sample MCQs and reviewing the answers can help candidates identify areas where they may need to improve their knowledge or skills.
Overall, the MCQs for lab technologists are designed to be challenging and comprehensive, requiring candidates to demonstrate a high level of proficiency in the field of laboratory science.
