The Total Iron Binding Capacity (TIBC) Calculator helps evaluate your body’s iron metabolism by measuring how much iron your blood can transport. This tool is essential for diagnosing iron-related disorders like anemia, hemochromatosis, and chronic diseases.
- Key Features:
- Calculates TIBC using Serum Iron and Unsaturated Iron Binding Capacity (UIBC).
- Determines Transferrin Saturation to assess iron utilization.
- Provides normal reference ranges and interprets results for clinical conditions.
Formula
TIBC (μg/dL) = Serum Iron (μg/dL) + UIBC (μg/dL)
Alternative (if transferrin is measured):
TIBC (μg/dL) = Transferrin (mg/dL) × 1.25
How to Use the Calculator
- Input Values:
- Serum Iron (from lab results, in μg/dL).
- UIBC (from lab results, in μg/dL).
- Calculate TIBC:
TIBC (μg/dL) = Serum Iron (μg/dL) + UIBC (μg/dL)
Example Calculation
- Serum Iron = 60 μg/dL
- UIBC = 340 μg/dL
TIBC (μg/dL) = 60 + 340 = 400 μg/dL
🧮 Total Iron Binding Capacity (TIBC) Calculator
🧪 Formula Used:
TIBC (μg/dL) = Serum Iron (μg/dL) + UIBC (μg/dL)
UIBC = Unsaturated Iron Binding CapacityNormal Ranges
| Parameter | Normal Range |
|---|---|
| TIBC | 240–450 μg/dL |
| Serum Iron | 60–170 μg/dL (men) 50–150 μg/dL (women) |
| Transferrin Saturation | 20–50% |
Clinical Interpretation
| TIBC Result | Possible Conditions |
|---|---|
| High TIBC (>450 μg/dL) | Iron deficiency anemia, pregnancy, chronic blood loss |
| Low TIBC (<240 μg/dL) | Chronic inflammation, liver disease, hemochromatosis |
Transferrin Saturation Formula:
Transferrin Saturation (%) =
(
Serum Iron
TIBC
)
× 100
Example:
- Iron : 60 μg/dL
- TIBC: 400 μg/dL
Transferrin Saturation (%) =
(
60 μg/dL
400 μg/dL
)
× 100 = 15%
Key Notes
- Units Matter: Ensure Serum Iron and UIBC are in μg/dL.
- High TIBC + Low Serum Iron = Iron deficiency anemia.
- Low TIBC + High Serum Iron = Hemochromatosis or iron overload.
- Normal TIBC + Low Serum Iron = Anemia of chronic disease.
Quick Reference Table
| Condition | TIBC | Serum Iron | Transferrin Saturation |
|---|---|---|---|
| Iron Deficiency | ↑↑ | ↓↓ | ↓ (<15%) |
| Hemochromatosis | ↓ | ↑↑ | ↑ (>50%) |
| Chronic Disease | ↓/Normal | ↓ | Normal/Low |
Calculate TIBC to unravel iron metabolism disorders and guide treatment!
Data sourced from WHO and American Society of Hematology guidelines.
