7001 to 7050 MCQs for Lab Technician and Technologist Exam Preparation
5000 Plus MCQs for Lab Technician and Technologists are designed to test the knowledge and proficiency of laboratory professionals who work in the field of clinical laboratory science. These questions cover a wide range of topics related to laboratory science, including anatomy, physiology, microbiology, chemistry, and hematology.
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Questions 7001 to 7050
- Which of the following amino acid has been shown as one of the active site of phosphoglucomutase?
- Lysine
- Tyrosine
- Serine ✔
- Histidine
- The inhibition of succinate dehydrogenase by malonate by
- Competitive inhibition ✔
- Non-competitive inhibition
- Uncompetitive inhibition
- Feedback inhibition
- Cobamide coenzymes are
- Vitamin B1
- Riboflavin
- Pyridoxine
- Vitamin B12 ✔
- The isozyme CK-MB is specifically increased in the blood of patients who had
- Skeletal muscle disease
- Recent myocardial infarction ✔
- Infective hepatitis
- Myxoedema
- FAD containing enzyme, catalyzing formation of α, β unsaturated fatty acyl CoA derivative.
- Acyl CoA dehydrogenase ✔
- Enoyl hydrase
- β-OH acyl CoA dehydrogenase
- Thiolase
- Immobilized enzymes:
- Potentiation of activity
- Presentation of activity ✔
- Preparation of activity
- All of these
- This catalyzes formation of CoA derivatives from fatty acid, CoA and ATP:
- Acyl CoA dehydrogenase
- Enoyl hydrase
- β-OH acyl CoA dehydrogenase
- Thio kinase ✔
- Fructose 2, 3 bi phosphate is a powerful allosteric activator of
- Fructose 1, 6 diphosphatase
- Phosphofructokinase ✔
- Hexokinase
- Fructokinase
- ‘Clearing factor’ is
- Lipoprotein lipase ✔
- Crotonase
- 7-dehydro cholesterol
- β-sitosterol
- Maltase attacks only
- α-glucosides ✔
- β-glucosides
- Starch
- Dextrins
- Pepsin is
- Exo-peptidase
- Endo-peptidase ✔
- Carboxy peptidase
- Amino peptidase
- An enzyme in saliva which hydrolyzes starch is
- Pepsinogen
- Chymotrysin
- α-Amylase ✔
- Malate
- If a coenzyme is required in an enzyme reaction, the former usually has the function of
- Acting as an acceptor for one of the cleavage products of the substrate ✔
- Enhancing the specificity of the apo enzyme
- Increasing the number of receptor sites of the apo enzyme
- Activating the substrate
- The Michaehis-Menten hypothesis:
- Postulates the formation of an enzyme substrate complex ✔
- Enables us to calculate the isoelectric point of an enzyme
- States that the rate of a chemical reaction may be independent of substrate concentration
- States that the reaction rate is proportional to substrate concentration
- Schardinger’s enzyme is
- Lactate dehydrogenase
- Xanthine dehydrogenase ✔
- Uric oxidase
- L amino acid dehydrogenase
- Tryptophan pyrolase is currently known as
- Tryptophan deaminase
- Tryptophan dioxygenase ✔
- Tryptophan mono oxygenase
- Tryptophan decarboxylase
- An enzyme which brings about lysis of bacterial cell wall is
- Amylase
- Lysozyme✔
- Trypsin
- Lipase
- Trypsin has no action on
- Hemoglobin
- Albumin
- Histone
- DNA ✔
- Multiple forms of the same enzymes are known as
- Zymogens
- Isoenzymes ✔
- Proenzymes
- Pre-enzymes
- In non-competitive enzyme action
- Vmax is increased
- Apparent km is increased
- Apparent km is decreased ✔
- Concentration of active enzyme molecule is reduced
- An allosteric enzyme influences the enzyme activity by
- Competiting for the catalytic site with the substrate
- Changing the specificity of the enzyme for the substrate
- Changing the conformation of the enzyme by binding to a site other than catalytic site ✔
- Changing the nature of the products formed
- A competitive inhibitor of an enzyme haswhich of the following properties?
- It is frequently a feedback inhibitor
- It becomes covalently attached to an enzyme
- It decreases the Vmax
- It interferes with substrate binding to the enzyme ✔
- When [s] is equal to Km, which of the following conditions exist?
- Half the enzyme molecules are bound to substrate ✔
- The velocity of the reaction is equal to Vmax
- The velocity of the reaction is independent of substrate concentration
- Enzyme is completely saturated with substrate
- Which of the following statements about an enzyme exhibiting allosteric kinetics with cooperative interaction is false?
- A plot of V-Vk [s] has a sigmaidal shape
- An inhibitor may increase the apparent Km
- Line weaver Bnrk plot is useful for determining Km and Vmax ✔
- Removal of allosteric inhibitor may result in hyperbolic V-S [s] plot
- Pantothenic acid acts on
- NADP
- NADPH
- FAD
- CoA ✔
- Vitamin deficiency that causes fatty liver includes all except
- Vitamin E
- Pyridoxine✔
- Retionic acid
- Pantothenic acid
- In which of the following types of enzymes an inducer is not required?
- Inhibited enzyme
- Cooperative enzyme
- Allosteric enzyme
- Constitutive enzyme ✔
- In which of the following types of enzyme water may be added to a C—C double bond without breaking the bond?
- Hydrolase
- Hydratase ✔
- Hydroxylase
- Esterase
- ‘Lock’ and ‘Key’ model of enzyme action proposed by Fisher implies that
- The active site is flexible and adjusts to substrate
- The active site requires removal of PO4 group
- The active site is complementary in shape to that of the substrate ✔
- Substrates change conformation prior to active site interaction
- In competitive inhibition of enzyme action
- The apparent Km is decreased
- The apparent Km is increased ✔
- Vmax is decreased
- Apparent concentration of enzyme molecules decreased
- In competitive inhibition which of the following kinetic effect is true ?
- Decreases both Km and Vmax
- Increases both Km and Vmax
- Decreases Km without affecting Vmax
- Increases Km without affecting Vmax ✔
- Enzymes increase the rates of reactions by
- Increasing the free energy of activation
- Decreasing the energy of activation ✔
- Changing the equilibrium constant of the reaction
- Increasing the free energy change of the reaction
- The most useful test for the diagnosis of acute hemorrhagic pancreatitis during the first few days is
- Urinary lipase test
- Serum calcium
- Urinary amylase
- Serum amylase ✔
- The best test for acute pancreatitis in the presence of mumps is
- A serological test for mumps
- Serum amylase
- Urinary amylase
- Serum lipase ✔
- The slow moving fraction of LDH is typically increased in pancreas with
- Cerebrovascular accidents
- Acute myocardial infarction
- Acute pancreatitis ✔
- Acute viral hepatits
- Which of the following enzyme typically elevated in alcoholism?
- Serum ALP
- Serum GOT
- Serum γ-GT ✔
- Serum acid phosphatase
- Patients with hepatocellular jaundice, as compared to those with purely obstructive jaundice tend to have
- Lower serum ALP, LDH and AST activity
- Lower serum ALP, Higher LDH and AST activity ✔
- Higher serum ALP, LDH and AST activity
- Higher serum ALP, Lower LDH and AST activity
- If results of the serum bilirubin, serum ALP, LDH and AST determinations suggest obstructive jaundice, the best confirmatory test would be the estimation of
- Serum ALT
- Serum 5’ nucleotidase ✔
- Serum Pseudo cholinesterase
- None of these
- Which enzyme estimation will be helpful in differentiating the elevated serum ALP found in obstructive jaundice as well as bone disorders?
- Serum AST
- Serum ALT
- Serum LDH
- Serum γ-GT ✔
- Cardiac muscle contains which of the following CK osoenzyme?
- BB only
- MM and BB only
- MM, BB and MB
- MM and MB only ✔
- Liver and skeletol measle disorders are characterized by on disk proportionate increase in which of the LDH isoenzyme fraction?
- LDH-1
- LDH-1 and LDH-2
- LDH-3 and LDH-4
- LDH-2 and LDH-3 ✔
- LDH-5
- On the third day following onset of acute myocardial infarction, which enzyme estimation will have the best predictive value?
- Serum AST
- Serum CK
- Serum ALT
- Serum LDH ✔
- Serum AST activity is not characteristically elevated as the result of
- Myocardial infarction
- Passive congestion of liver
- Muscular dystrophies
- Peptic ulcer ✔
- On which day following acute myocardial infarction the estimation of serum AST will be of greatest significance?
- First day
- Second day ✔
- Third day
- Fourth day
- In which diseases of the following organs, isoenzymes LDH-1 and LDH-2 will be released in plasma?
- Kidney, R.B.C and Liver
- Heart, Kidney and R.B.C ✔
- Heart, Kidney and Liver
- Heart, Lungs and Brain
- Plasma non-functional enzymes are
- totally absent
- low concentration in plastic
- important for diagnosis of several disease ✔
- All of these
- Pyruvate dehydrogenase contains all except
- Biotin ✔
- NAD
- FAD
- CoA
- An increase in LDH-5 enzyme is seen in the following except
- Acute hepatitis
- Muscular distrophies
- Breast carcinoma
- Pulmonary embolism ✔
- Diastase can be used for the hydrolysis can be used for the hydrolysis of
- Sucrose
- Starch ✔
- Cellulose
- Maltose
- Which of the following statements is true?
- Enzymes have names ending ase
- Enzymes are highly specific in their action ✔
- Enzymes are living organisms
- Enzymes get activated on heating
The questions are typically designed to assess the technical skills and knowledge required for the laboratory profession, including the ability to analyze laboratory test results, perform laboratory procedures, and maintain laboratory equipment.
To prepare for these MCQs, candidates should have a thorough understanding of the key concepts and principles of laboratory science. They should also be familiar with common laboratory equipment and procedures, as well as laboratory safety protocols.
Candidates may also benefit from studying specific laboratory science textbooks or taking online courses that cover the material tested in the MCQs. Additionally, practicing sample MCQs and reviewing the answers can help candidates identify areas where they may need to improve their knowledge or skills.
Overall, the MCQs for lab technologists are designed to be challenging and comprehensive, requiring candidates to demonstrate a high level of proficiency in the field of laboratory science.
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