6751 to 6800 MCQs for Lab Technician and Technologist Exam Preparation
5000 Plus MCQs for Lab Technician and Technologists are designed to test the knowledge and proficiency of laboratory professionals who work in the field of clinical laboratory science. These questions cover a wide range of topics related to laboratory science, including anatomy, physiology, microbiology, chemistry, and hematology.

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Questions 6751 to 6800
- Essential fructosuria is characterized by the lack of the hepatic enzyme:
- Phosphohexose isomerase
- Aldalose A
- Aldolase B
- Fructokinase ✔
- In normal individuals glycosuria occurs when the venous blood glucose concentration exceeds
- 5–6 mmol/L
- 7–8 mmol/L
- 8.5–9 mmol/L
- 9.5–10 mmol/L ✔
- Renal glycosuria is characterized by
- Hyperglycemia
- Hyperglycemia with glycosuria
- Normal blood glucose level with glycosuria ✔
- Hyperglycemia with ketosis
- Acute hemolytic anemia in person’s sensitive to the Fava beans is due to the deficiency of the enzyme:
- Pyruvate dehydrogenase
- G-6-PD ✔
- Aconitase
- Transketolase
- Acute hemolytic episode after administration of antimalarial, primaquin, is due to deficiency of the enzyme:
- 6-Phosphogluconate dehydrogenase
- Glucose-6-phosphate dehydrogenase ✔
- Epimerase
- Transketolase
- The pH optima of gastric lipase is
- 3.0–6.0 ✔
- 1.0–2.0
- 8.0
- 8.6
- The optimum pH of pancreatic lipase is
- 2.0
- 4.0
- 6.0
- 8.0 ✔
- Gastric lipae is activated in the presence of
- Bile salts ✔
- Cu++
- K+
- Na+
- An example of enzyme inhibition:
- Reversible inhibition
- Irreversible inhibition
- Allosteric inhibition
- All of these ✔
- The formation of ∆2-trans-enoyl-CoA from acyl-CoA requires the enzyme:
- Acyl-CoA synthetase
- Acyl-CoA dehydrogenase ✔
- 3-Hydroxy acyl-CoA dehydrogenase
- Thiolase
- In β-oxidation 3-ketoacyl-CoA is splitted at the 2, 3 position by the enzyme:
- Hydratase
- Dehydrogenase
- Reducatse
- Thiolase ✔
- Fatty acids with odd number of carbon atoms yield acetyl-CoA and a molecule of
- Succinyl-CoA
- Propionyl-CoA ✔
- Malonyl-CoA
- Acetoacetyl-CoA
- The net gain of ATP/mol of palmitic acid on complete oxidation is
- 88
- 105
- 129 ✔
- 135
- ω-oxidation is normally a very minor pathway and is brought by hydroxylase enzymes involving
- Cytochrome a
- Cytochrome b
- Cytochrome c
- Cytochrome p-450✔
- α-Oxidation i.e., the removal of one carbon at a time from the carboxyl end of the molecule has been detected in
- Brain tissue ✔
- Liver
- Adipose tissue
- Intestine
- In β-oxidation, the coenzyme for acyl-CoA dehydrogenase is
- FMN
- NAD
- NADP
- FAD ✔
- The coenzyme involved in dehydrogenation of 3-hydroxy acyl-CoA is
- FAD
- FMN
- NAD ✔
- NADP
- The concentration of ketone bodies in the blood does not normally exceed
- 0.2 mmol/L ✔
- 0.4 mmol/L
- 1 mmol/L
- 2 mmol/L
- In humans under normal conditions loss of ketone bodies via urine is usually less than
- 1 mg/24 hr✔
- 4 mg/24 hr
- 8 mg/24 hr
- 10 mg/24 hr
- The structure which appears to be the only organ to add significant quantities of ketone bodies to the blood is
- Brain
- Erythrocytes
- Liver ✔
- Skeletal muscle
- The starting material for ketogenesis is
- Acyl-CoA
- Acetyl-CoA✔
- Acetoacetyl-CoA
- Malonyl-CoA
- Enzymes responsible for ketone body formation are associated mainly with the
- Mitochondria ✔
- Endoplasmic reticulum
- Nucleus
- Golgi apparatus
- In the pathway leading to biosynthesis of acetoacetate from acetyl-CoA in liver, the immediate precursor of aceotacetate is
- Acetoacetyl-CoA ✔
- 3-Hydroxybutyryl-CoA
- 3-Hydroxy-3-methyl-glutaryl-CoA
- 3-Hydroxybutyrate
- Ketone bodies serve as a fuel for
- Extrahepatic tissues ✔
- Hepatic tissues
- Erythrocytes
- Mitochondria
- In extra hepatic tissues, one mechanism for utilization of acetoacetate involves
- Malonyl-CoA
- Succinyl-CoA ✔
- Propionyl-CoA
- Acetyl-CoA
- Ketosis reflects
- Increased hepatic glucose liberation
- Increased fatty acid oxidation ✔
- Increased carbohydrate utilisation
- Incresed gluconeogenesis
- Ketosis is associated with the disease:
- Nephritis
- Diabetes mellitus ✔
- Edema
- Coronary artery diseases
- The main pathway for denovo synthesis of fatty acids occur in
- Cytosol ✔
- Mitochondria
- Microsomes
- Nucleus
- Chain elongation of fatty acids in mammalian liver occurs in
- Nucleus
- Ribosomes
- Lysosomes
- Microsomes ✔
- Acetyl-CoA is the principal building block of fatty acids. It is produced within the mitochondria and does not diffuse readily into cytosol. The availability of acetyl CoA involves
- Carnitine acyl transferase
- Pyruvate dehydrogenase
- Citrate lyase ✔
- Thiolase
- The synthesis of fatty acids is often termed reductive synthesis.
- NADP+
- NADH ✔
- FADH2
- NADPH
- The protein, which is in fact a multifunctional enzyme complex in higher organism is
- Acetyl transacylase
- Malonyl transacylase
- 3-Hydroxy acyl-ACP dehyratase
- Fatty acid synthase ✔
- The fatty acid synthase complex catalyses
- 4 sequential enzymatic steps
- 6 sequential enzymatic steps
- 7 sequential enzymatic steps ✔
- 8 sequential enzymatic steps
- The main source of reducing equivalents (NADPH) for lipogenesis is
- Pentose phosphate pathway ✔
- Citric acid cycle
- Glycolysis
- Glycogenolysis
- In fatty acids synthase of both bacteria and mammals, ACP (acyl carrier protein) contain the vitamin:
- Thiamin
- Pyridoxine
- Riboflavin
- Pantothenic acid ✔
- Carboxylation of acetyl-CoA to malonylCoA requires the enzyme:
- Acetyl-CoA carboxylase ✔
- Pyruvate carboxylase
- Acetyl transacylase
- Acyl CoA-synthetase
- The rate limiting reaction in the lipogenic pathway is
- Acetyl-CoA carboxylase step✔
- Ketoacyl synthase step
- Ketoacyl reductase step
- Hydratase step
- Conversion of fatty acyl-CoA to an acylCoA derivative having 2 more carbon atoms involves as acetyl donar:
- Acetyl-CoA
- Succinyl-CoA
- Propionyl-CoA
- Malonyl-CoA ✔
- A cofactor required for the conversion of acetyl-CoA to malonyl-CoA in extramitochondrial fatty acid synthesis is
- Biotin ✔
- FMN
- NAD
- NADP
- The glycerol for fatty acid esterification in adipocytes is
- For the most part, derived from glucose ✔
- Obtained primarily from phosphorylation of glycerol by glycerol kinase
- Formed from gluconeogenesis
- Formed from glycogenolysis
- In the biosynthesis of triglycerides from glycerol 3-phosphate and acyl-CoA, the first intermediate formed is
- 2-Monoacylglycerol
- 1, 2-Diacylglycerol
- Lysophosphatidic acid
- Phosphatidic acid ✔
- The enzyme glycerol kinase is low activity in
- Liver
- Kidney
- Intestine
- Adipose tissue ✔
- The common precursor in the biosynthesis of triacylglycerol and phospholipids is
- 1, 2-Diacylglycerol phosphate
- 1-Acylglycerol 3-phosphate
- Glycerol 3-phosphate ✔
- Dihydroxyacetone phosphate
- Synthesis of polyunsaturated fatty acids involves the enzyme systems:
- Acyl transferase and hydratase
- Desaturase and elongase ✔
- Ketoacyl-CoA reductase and hydratase
- Dihydroxyacetone phosphate
- The desaturation and chain elongation system of polyunsaturated fatty acid are enhanced by
- Insulin ✔
- Glucagon
- Epinephrine
- Thyroxine
- Higher rate of lipogenesis is associated with
- High proportion of carbohydrate in diet ✔
- Restricted caloric intake
- High fat diet
- Deficiency of insulin
- Example of enzyme specificity:
- Stereo specificity
- Reaction specificity
- Substrate specificity
- All of these ✔
- Phospholipase C attacks the ester bond liberating 1, 2-diacylglycerol and a phosphoryl base at position
- 1
- 2
- Both (1) and (2)
- 3 ✔
- Synthesis of phosphatidylinositol by transfer of inositol to CDP diacylglycerol is catalysed by the enzyme:
- CTP phosphatidate cytidyl transferase
- Phosphatidate phosphohydrolase
- CDP-diacylglycerol inositol transferase ✔
- Choline kinase
- Synthesis of sphingosine requires the cofactor
- NAD
- NADP
- NADPH+ ✔
- ATP
The questions are typically designed to assess the technical skills and knowledge required for the laboratory profession, including the ability to analyze laboratory test results, perform laboratory procedures, and maintain laboratory equipment.
To prepare for these MCQs, candidates should have a thorough understanding of the key concepts and principles of laboratory science. They should also be familiar with common laboratory equipment and procedures, as well as laboratory safety protocols.
Candidates may also benefit from studying specific laboratory science textbooks or taking online courses that cover the material tested in the MCQs. Additionally, practicing sample MCQs and reviewing the answers can help candidates identify areas where they may need to improve their knowledge or skills.
Overall, the MCQs for lab technologists are designed to be challenging and comprehensive, requiring candidates to demonstrate a high level of proficiency in the field of laboratory science.
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