Search Here

Immunoglobulin M (IgM)

One of the five classes of immunoglobulins; a large molecule, it is found in blood and is involved in combating blood infections. It is the first or primary immunoglobulin produced following exposure to an antigen.

Immunoglobulin M (IgM)

Immunoglobulin M (IgM), which is found mainly in the blood and lymph fluid, is the first antibody to be made by the body to fight a new infection.

email_subscription

Receive all our future posts instantly in your inbox. Enter your email to enroll.

Sample 

  • Fresh serum of the patient is needed.
  • Analyze the sample as soon as possible or can store at 4 °C for a few hours (less than 72 hours).
  • The sample is stable at -20 °C for 6 months.

Indications

  1. Used to detect monoclonal gammopathy.
  2. It is advised in immune deficiencies.

Normal Value:

  • Adult = 55 to 375 mg/dL
  • Children = 20 to 200 mg/dL

Decreased level of IgM seen in:

  • Decreased level seen in congenital deficiency diseases.

Increased level of IgM seen in :

  1. Elevations of IgM may be due to polyclonal immunoglobulin production which was seen in various infections.
  2. An isolated increase in IgM level may be seen in viral infections e.g. Viral hepatitis, infectious mononucleosis, and early response to bacterial or parasitic infection.
  3. Increased level of IgM may be seen in Rheumatoid arthritis, biliary cirrhosis, and some other chronic disorders.
  4. Raised levels are also seen in Hyper IgM dysgammaglobulinemia, active sarcoidosis, collagen vascular diseases, nephrotic syndrome.
  5. Monoclonal  raised levels are seen in :
    1. Waldenstrom’s globulinemia.
    2. Lymphomas.

Related Articles:

  • Autoclave sterilization is a moist heat sterilizing technique that is commonly used in laboratories, industries, […]
  • Motility test can define as the analytical method, which examines whether the bacteria are motile […]
  • Anti-Mullerian Hormone (AMH) is a protein hormone produced by cells within the ovary. Understanding your […]
  • List of Abbreviations produced by Clinical Staff for use within Health Records. To support … PAEDIATRIC THERAPIES TEST ABBREVIATIONS. Test […]
  • Bacteria and viruses are the culprit of many common infections. However, there are differences between […]
  • Sterilization means the freeing of an article from all organism including viruses, bacteria and their […]
  • Your pancreas produces an enzyme called lipase. When you eat, lipase is released into your […]
  • Amylase is an enzyme, or special protein, produced by your pancreas and salivary glands. The […]


Possible References Used


Leave a Reply

Your email address will not be published. Required fields are marked *

Navigate: Home | Categories | About Us | Authors | Contact Us | Submit News Tips | Advertise | Write for Us
Find us on: Facebook | Twitter | Tumblr | YouTube | Reddit | Pinterest | Instagram
More: RSS | Sitemap | Back to: Top
© 2018-2020 Lab Tests Guide