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Blood Bank - Selection of Donors General considerations Medical assessment Medical history of donors Conditions necessitating permanent exclusion Conditions necessitating temporary deferral Pregnancy Donors on treatment with drugs Infectious diseases Tropical diseases Inoculations and immunisations Physical examination of donors Quality Assurance at Blood Donor Sessions General specifications Records Documentation Control of purchased materiel and services Collection control Preservation of product quality. General Guidelines for Component Manufacture Scope of the Guidelines Setting and maintenance of specifications Component and process monitoring tests Component processing Component shelf life Component labelling Component storage Discard of non-conforming components Component release Transport of blood components Component recal1 Guideline Specifications for Blood Components Whole blood Red cells in additive solution Red cells, leucocyte depleted Red cells, washed Platelets Platelets, pooled, leucocyte depleted Platelets, apheresis Platelets, apheresis, leucocyte depleted Granulocytes, Apheresis Fresh frozen plasma Cryoprecipitate Cryosupernatant Plasma Components for neonates Irradiated components General Specifications for Donor Sessions Donor identification Haemoglobin or haematocrit screening Preparation of the venepuncture site Preparation of the blood pack Performance of the venepuncture Blood donation Declaration of health Premises General considerations Activities to be noted when selecting venue(s) for mobile session Health and safety factors to be considered Specifications for Laboratory Test Procedures General Considerations Scope Test reagents, kits and equipment Reporting results Release of tested components Mandatory Testing of Blood Donations Blood group serology tests Microbiology tests Additional Testing of Selected Donations Antibody to cytomegalovirus Requirements for Safe and Effective Transportation of Blood and Blood Components. Transportation between donor sessions and blood centre Whole blood and red cell components Platelet Plasma components Transfer between centers or hospitals Requirements for Blood Bag Labels General Guidelines for Serological Tests Introduction Grading system for agglutination tests Test Red Cells Test tubes Centrifugation following the addition of AHG reagent. Centrifugation and reading serological tests. Non-serological tests Specificity tests Serological Guidelines for ABO and RhD Blood Grouping Reagents Introduction Potency of ABO blood grouping reagents used in manual or microplate tests Potency of ABO blood grouping reagents used in manual or microplate tests Avidity of ABO blood grouping reagents for use in manual slide tests Specificity of anti-D blood grouping reagents used in manual or microplate tests. Potency of anti-D blood grouping reagents used in manual or microplate tests, Avidity of anti-D blood grouping reagents for use in manual slide tests Guidelines for Reagent Red Cells Guidelines for testing reagent red cells Preparation of reagent red cells Enzyme- treated reagent red cells Reagent red cells for use in ABO grouping Reagent red cells for use in RhD grouping Reagent red cells for use in antibody screening Reagent red cells for use in antibody identification Reagent red cells for use in the control of the anti- human globulin technique Guidelines for Clinical use of Blood and Blood Products Red Cell Preparations Platelet Concentrates Plasma Albumin Intra Venous (IV) Immune Globuline Hemophilia Treatment.
  1. Selection of Donors
    • General considerations
    • Medical assessment
    • Medical history of donors
    • Conditions necessitating permanent exclusion
    • Conditions necessitating temporary deferral
    • Pregnancy
    • Donors on treatment with drugs
    • Infectious diseases
    • Tropical diseases
    • Inoculations and immunisations
    • Physical examination of donors
  2. Quality Assurance at Blood Donor Sessions
    • General specifications
    • Records
    • Documentation
    • Control of purchased materiel and services
    • Collection control
    • Preservation of product quality.
  3. General Guidelines for Component Manufacture
    • Scope of the Guidelines
    • Setting and maintenance of specifications
    • Component and process monitoring tests
    • Component processing
    • Component shelf life
    • Component labelling
    • Component storage
    • Discard of non-conforming components
    • Component release
    • Transport of blood components
    • Component recal1
  4. Guideline Specifications for Blood Components
    • Whole blood
    • Red cells in additive solution
    • Red cells, leucocyte depleted
    • Red cells, washed
    • Platelets
    • Platelets, pooled, leucocyte depleted
    • Platelets, apheresis
    • Platelets, apheresis, leucocyte depleted
    • Granulocytes, Apheresis
    • Fresh frozen plasma
    • Cryoprecipitate
    • Cryosupernatant Plasma
    • Components for neonates
    • Irradiated components
  5. General Specifications for Donor Sessions
    • Donor identification
    • Haemoglobin or haematocrit screening
    • Preparation of the venepuncture site
    • Preparation of the blood pack
    • Performance of the venepuncture
    • Blood donation
    • Declaration of health
  6. Premises
    • General considerations
    • Activities to be noted when selecting venue(s) for mobile session
    • Health and safety factors to be considered
  7. Specifications for Laboratory Test Procedures
    • General Considerations
      1. Scope
      2. Test reagents, kits and equipment
      3. Reporting results
      4. Release of tested components
    • Mandatory Testing of Blood Donations
      1. Blood group serology tests
      2. Microbiology tests
    • Additional Testing of Selected Donations
      1. Antibody to cytomegalovirus
  8. Requirements for Safe and Effective Transportation of Blood and Blood Components.
    • Transportation between donor sessions and blood centre
    • Whole blood and red cell components
    • Platelet
    • Plasma components
    • Transfer between centers or hospitals
  9. Requirements for Blood Bag Labels
  10. General Guidelines for Serological Tests
    • Introduction
    • Grading system for agglutination tests
    • Test Red Cells
    • Test tubes
    • Centrifugation following the addition of AHG reagent.
    • Centrifugation and reading serological tests.
    • Non-serological tests
    • Specificity tests
  11. Serological Guidelines for ABO and RhD Blood Grouping Reagents
    • Introduction
    • Potency of ABO blood grouping reagents used in manual or microplate tests
    • Potency of ABO blood grouping reagents used in manual or microplate tests
    • Avidity of ABO blood grouping reagents for use in manual slide tests
    • Specificity of anti-D blood grouping reagents used in manual or microplate tests.
    • Potency of anti-D blood grouping reagents used in manual or microplate tests,
    • Avidity of anti-D blood grouping reagents for use in manual slide tests
  12. Guidelines for Reagent Red Cells
    • Guidelines for testing reagent red cells
    • Preparation of reagent red cells
    • Enzyme- treated reagent red cells
    • Reagent red cells for use in ABO grouping
    • Reagent red cells for use in RhD grouping
    • Reagent red cells for use in antibody screening
    • Reagent red cells for use in antibody identification
    • Reagent red cells for use in the control of the anti- human globulin technique
  13. Guidelines for Clinical use of Blood and Blood Products
    • Red Cell Preparations
    • Platelet Concentrates
    • Plasma
    • Albumin
    • Intra Venous (IV) Immune Globuline
    • Hemophilia Treatment.

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