The Albumin-Globulin (A/G) Ratio Calculator evaluates the balance between albumin and globulin proteins in blood, aiding in the diagnosis of liver disease, kidney disorders, and immune system conditions.
Formula:
A/G Ratio =
Albumin (g/dL)
Total Protein (g/dL) – Albumin (g/dL)
Or
A/G Ratio =
Albumin (g/dL)
Globulin (g/dL)
Note: Globulin is often calculated as:
Globulin (g/dL) = Total Protein (g/dL) – Albumin (g/dL)
🧮 Albumin-Globulin (A/G) Ratio Calculator
📐 Formula:
A/G Ratio =
Albumin (g/dL)
Total Protein (g/dL) - Albumin (g/dL)
🖊️ Enter the Values:
Step-by-Step Calculation
- Input Lab Values:
- Albumin (g/dL) = 4.0
- Total Protein (g/dL) = 7.0
- Calculate Globulin (if needed):
Globulin (g/dL) = Total Protein (g/dL) – Albumin (g/dL)
Globulin (g/dL) = 7.0 (g/dL) – 4.0 (g/dL) = 3.0 (g/dL) - Compute A/G Ratio:
A/G Ratio =
Albumin (g/dL)
Total Protein (g/dL) – Albumin (g/dL)
A/G Ratio =
4.0 (g/dL)
7.0 (g/dL) – 4.0 (g/dL)
A/G Ratio =
4.0 (g/dL)
3.0 (g/dL)
= 1.33
Normal Range
| Group | Normal A/G Ratio |
|---|---|
| Adults | 1.1–2.5 |
Clinical Interpretation
| A/G Ratio | Possible Conditions |
|---|---|
| High (>2.5) | – Dehydration – Hyperalbuminemia – Hypogammaglobulinemia |
| Low (<1.1) | – Liver cirrhosis – Nephrotic syndrome – Chronic inflammation – Multiple myeloma |
Example Scenarios
| Albumin (g/dL) | Globulin (g/dL) | A/G Ratio | Interpretation |
|---|---|---|---|
| 4.5 | 2.5 | 1.8 | Normal |
| 3.0 | 4.0 | 0.75 | Low (Liver/kidney disease) |
| 5.2 | 1.8 | 2.9 | High (Dehydration) |
Key Notes
- Albumin: Maintains osmotic pressure; synthesized by the liver.
- Globulins: Include antibodies (immunoglobulins), enzymes, and transport proteins.
- Critical Use Cases:
- Evaluate liver/kidney dysfunction.
- Screen for multiple myeloma (low A/G ratio with elevated globulins).
- Limitations:
- Non-specific – always correlate with clinical symptoms and other tests (e.g., LFTs, SPEP).
Quick Reference Table
| Test | Normal Range | Role |
|---|---|---|
| Albumin | 3.5–5.5 g/dL | Reflects liver function |
| Total Protein | 6.0–8.3 g/dL | Includes albumin + globulin |
| Urine Protein Electrophoresis | – | Diagnose myeloma/kidney disease |
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The content on LabTestsGuide.com is for informational and educational purposes only. We do not guarantee the accuracy, completeness, or timeliness of the information provided. Always consult qualified healthcare professionals for medical advice, diagnosis, or treatment. LabTestsGuide.com is not liable for any decisions made based on the information on this site.
