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MCQ’s Chapter 4 (Doctors)

Some of Common Questions and Answers for Doctors and Medical Students.

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Chapter 4
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Questions 151 to 200

  1. At 28 weeks gestation where would you expect to feel the uterine fundus?
    1. Symphysis pubis
    2. Umbilicus
    3. Xiphisternum
    4. Halfway between xiphisternum and umbilicus
  2. Which of the following is thought to be a cause of hyperemesis gravidarum?
    1. High levels of circulating HCG
    2. Underlying infection
    3. Over eating
    4. Psychological issues
  3. Which of the following methods is the correct way to calculate the estimated date of delivery (EDD)?
    1. First day of LMP + 9 months and 1 week
    2. Last day of LMP + 8 months and 1 week
    3. First day of LMP + 9 months
    4. First day of last menstrual period (LMP) + 8 months and 1 week
  4. Which period of gestation does the 2nd trimester represent?
    1. 13-28 weeks
    1. 15-30 weeks
    2. 14-29 weeks
    3. 10-20 weeks
  5. At 36 weeks gestation where would you expect to find the uterine fundus?
    1. Halfway between umbilicus and xiphisternum
    2. Symphysis pubis
    3. Umbilicus
    4. Xiphisternum
  6. At what stage of gestation would you expect a nulliparous women to begin to feel fetal movements?
    1. 14-16 weeks
    2. 18-20 weeks
    3. 10-12 weeks
    4. 22-24 weeks
  7. What is the most common cause of postpartum haemorrhage?
    1. Vulval or vaginal lacerations
    2. Retained placenta
    3. Uterine atony
    4. Uterine rupture
  8. Which period of gestation does the 1st trimester represent?
    1. 1-12 weeks
    2. 1-13 weeks
    3. 1-11 weeks
    4. 1-10 weeks
  9. Which of the following are risk factors for pre-eclampsia?
    1. First pregnancy
    2. Family history of pre-eclampsia in mother or sisters
    3. Obesity (BMI >35)
    4. Maternal age > 40
    5. Change of partner
    6. All of Above
  10. Which of the following is a prostaglandin commonly used in induction of labour?
    1. Labetalol
    2. Atenolol
    3. Misoprostol
  1. At 12 weeks gestation where would you expect to feel the uterine fundus?
    1. Xiphisternum
    2. Halfway between umbilicus and xiphisternum
    3. Symphysis pubis
    4. Umbilicus
  2. Which of the following are causes of Addison’s disease?
    1. Tuberculosis
    2. Autoimmune destruction of the adrenal cortex
    3. Adrenoleukodystrophy
    4. Pyelonephritis
  3. What is the most common cause for the overproduction of growth hormone in acromegaly?
    1. Hyperplasia of the pituitary stalk
    2. Pituitary adenoma
    3. Hypothalamic lesion
    4. Pituitary lesion
  4. Which one of the following hormones binds to the pituitary and stimulates the release of luteinizing hormone (LH) and follicle stimulating hormone (FSH)?
    1. Gonadotrophin releasing hormone (GnRH)
    2. Adrenocorticotropic hormone (ACTH)
    3. Corticotropic releasing hormone (CRH)
  5. Which one of the following statements describes the underlying pathology of Grave’s disease?
    1. Inflammation of the thyroid gland due to lymphocytic infiltration causes the stored thyroid hormones to be released into the circulation leading to hyperthyroidism.
    2. An autoimmune disease directed against thyroid stimulating hormone (TSH) receptors. The autoantibodies stimulate the TSH receptors causing increased T3 and T4 production.
    3. A benign tumour of the thyroid gland which produces excessive amounts of thyroid hormones.
    4. Consumption of ground beef which has been contaminated with thyroid tissue. The thyroid tissue contains metabolically active thyroid hormones which causes hyperthyroidism.
  6. Which one of the following statements is true regarding the prevalence of acromegaly?
    1. Acromegaly affects twice as many men than it does women
    2. Acromegaly effects a similar number of men and women
    3. Acromegaly affects twice as many women than men
  7. Which of the following statements best describes Cushing’s syndrome?
    1. Cushing’s syndrome refers to a disease process caused by abnormally low levels of aldosterone
    2. Cushing’s syndrome refers to a disease process caused by abnormally low levels of cortisol
    3. Cushing’s syndrome refers to a disease process caused by abnormally high levels of aldosterone
    4. Cushing’s syndrome refers to a disease process caused by abnormally high levels of cortisol
  8. Which of the following statements regarding Cushing’s syndrome is correct?
    1. Men are more likely to develop Cushing’s syndrome
    2. Women are more likely to develop Cushing’s syndrome
    3. The incidence of Cushing’s syndrome is distributed equally between sexes
  9. Which one of the following statements best describes an Addisonian crisis?
    1. Dangerously high levels of testosterone
    2. Severe adrenal insufficiency resulting in dangerously low serum testosterone levels
    3. Severe adrenal insufficiency resulting in dangerously low serum cortisol levels
    4. Dangerously high serum cortisol levels
  10. Which of the following hormones are produced in the anterior pituitary gland?
    1. Follicle-stimulating hormone (FSH)
    2. Growth hormone (GH)
    3. Oxytocin
    4. Thyroid-stimulating hormone (TSH)
    5. Vasopressin (antidiuretic hormone)
    6. Adrenocorticotrophic hormone (ACTH)
    7. Prolactin
    8. Luteinizing hormone (LH)
  11. In males which hormone stimulates Leydig cells to produce testosterone?
    1. Luteinizing hormone (LH)
    2. Follicle stimulating hormone (FSH)
  12. Which of the following statements correctly describes the pathophysiology of Cushing’s disease?
    1. Cushing’s disease results from a benign adrenal adenoma secreting excess ACTH. High levels of ACTH in turn cause increased production of cortisol from the adrenal cortex.
    2. Cushing’s disease results from a benign adrenal adenoma secreting excess levels of cortisol.
    3. Cushing’s disease results from a benign pituitary adenoma secreting excess levels of cortisol.
    4. Cushing’s disease results from a benign pituitary adenoma secreting excess ACTH. High levels of ACTH in turn causes increased production of cortisol from the adrenal cortex.
  13. Which of the following are Sertoli cells responsible for producing?
    1. Testosterone
    2. Gonadotrophin releasing hormone (GnRH)
    3. Androgen binding globulin (ABG)
    4. Oestrogen
  14. Which one of the following is acromegaly caused by?
    1. Overproduction of gonadotrophin releasing hormone (GnRH)
    2. Overproduction of vasopressin (antidiuretic hormone)
    3. Overproduction of adrenocorticotropic hormone (ACTH)
    4. Overproduction of growth hormone (GH)
  15. Which of the following are symptoms of Addison’s disease?
    1. Weight gain
    2. Diplopia
    3. Hyperpigmentation
    4. Weight loss
    5. Striae
    6. Postural hypotension
    7. Moon face
    8. Fatigue
  16. Which of the following are causes of nephrogenic diabetes insipidus?
    1. Post obstructive uropathy
    2. Amyloidosis
    3. Atenolol
    4. Mutations in the vasopressin (ADH) receptor gene
    5. Mutations in vasopressin gene
    6. Sheehan’s syndrome
    7. Lithium
  17. Which one of the following is the main function of aldosterone?
    1. Increase in blood volume
    2. Decrease in blood volume
  18. Which of the following investigations is the gold standard for diagnosing acromegaly?
    1. Growth hormone measurement
    2. Growth hormone releasing hormone measurement
    3. Oral glucose tolerance test + Growth hormone measurement
    4. Serum IGF1 measurement
  19. Which of the following statements best describes diabetes insipidus?
    1. Diabetes insipidus is a disease characterised by the passage of large volumes of dilute urine
    2. Diabetes insipidus is a disease characterised by the passage of small volumes of concentrated urine
    3. Diabetes insipidus is a disease characterised by the passage of small volumes of dilute urine
    4. Diabetes insipidus is a disease characterised by the passage of large volumes of concentrated urine
  20. What is the most common cause of Cushing’s syndrome?
    1. Glucocorticoid treatment (iatrogenic)
    2. Pituitary adenoma
    3. Adrenal adenoma
    4. Ectopic ACTH production
  21. Which of the following are not causes of neurogenic diabetes insipidus?
    1. Trauma
    2. Sheehan’s syndrome
    3. Meningitis
    4. Mutatations in the vasopressin gene
    5. Polycystic kidney disease
    6. Pituitary adenoma
    7. Mutatations in the vasopressin (ADH) receptor gene
  22. Which of the following does the adrenal cortex produce?
    1. Cortisol
    2. Adrenaline
    3. Noradrenaline
    4. Aldosterone
  23. Which of the following statements best describes Hashimoto’s thyroiditis?
    1. Inflammation of the thyroid gland as the result of a virus. The disease is often preceded by an upper respiratory tract infection.
    2. A destructive autoimmune disease caused by auto-reactive antibodies against thyroglobulin.
    3. Iodine deficiency
  24. In regard to the investigation of hyperthyroidism, which one of the following antibodies is specific to Grave’s disease?
    1. TSH receptor antibodies
    2. Thyroid peroxidase antibody
    3. Thyroglobulin antibody
  25. Which of the following causes of Cushing’s syndrome does the phrase “Cushing’s disease” specifically refer to ?
    1. Pituitary adenoma
    2. Ectopic ACTH production
    3. Adrenal adenoma
    4. Iatrogenic
  26. Which of the following is not a symptom of Cushing’s syndrome?
    1. Easy bruising
    2. Stretch marks
    3. Increased pigmentation of skin
    4. Acne
    5. Weight gain
  27. What of the following statements best describes a toxic thyroid adenoma?
    1. Inflammation of the thyroid gland due to lymphocytic infiltration causing stored thyroid hormones to be released into the circulation leading to hyperthyroidism.
    2. A malignant tumour of the thyroid gland which produces excessive amounts of thyroid hormones. These arise from the follicular cells of the thyroid gland.
    3. An autoimmune disease directed against thyroid stimulating hormone (TSH) receptors. The autoantibodies stimulate the TSH receptors causing increased T3 and T4 production
    4. A benign tumour of the thyroid gland which produces excessive amounts of thyroid hormones. These arise from the follicular cells of the thyroid.
  28. Which of the following are common symptoms of hyperthyroidism?
    1. Urinary frequency
    2. Diarrhoea
    3. Weight gain
    4. Weight loss
    5. Heat intolerance
    6. Tremor
  29. Which age group does acromegaly most commonly affect?
    1. 55-70 years
    2. 10-25 years
    3. 30-50 years
    4. 25-40 years
  30. What is Addison’s disease?
    1. Addison’s disease involves the overproduction of cortisol and aldosterone by the adrenal cortex.
    2. Addison’s disease involves the overproduction of androgens by the adrenal medulla.
    3. Addison’s disease is a long-term endocrine disorder in which the adrenal glands do not produce enough steroid hormones.
    4. Addison’s disease involves the underproduction of androgens by the adrenal medulla.
  31. Which of the following is the underlying problem in neurogenic diabetes insipidus?
    1. Overproduction of oxytocin
    2. Overproduction of prolactin
    3. Lack of prolactin
    4. Lack of oxytocin
    5. Overproduction of vasopressin (antidiuretic hormone)
    6. Lack of vasopressin (antidiuretic hormone)
  32. Which is a more sensitive measure of thyroid function?
    1. Thyroid stimulating hormone (TSH)
    2. Free T4
    3. Free T3
  33. Which of the following are symptoms of acromegaly?
    1. Headache
    2. Visual changes (double vision, reduced vision, tunnel vision)
    3. Abdominal distention
    4. Vomiting
    5. Excessive sweating (hyperhidrosis)
    6. Widespread rash
    7. Increased finger ring size
    8. Deepening voice
    9. Diarrhoea
    10. Paresthesia and weakness in the hands
  34. What is the most common cause of hyperthyroidism?
    1. Grave’s disease
    2. Toxic thyroid adenoma
    3. Toxic multinodular goitre
    4. Thyroiditis
  35. Which of the following hormones are stored in the posterior pituitary gland?
    1. Luteinizing hormone (LH)
    2. Growth hormone (GH)
    3. Thyroid stimulating hormone (TSH)
    4. Follicle stimulating hormone (FSH)
    5. Adrenocorticotropic hormone (ACTH)
    6. Oxytocin
    7. Prolactin
    8. Vasopressin (antidiuretic hormone)
  36. Which of the following are correct regarding the effects of increased levels of growth hormone in acromegaly?
    1. Increased levels of growth hormone stimulate increased production of insulin like growth factor one (IGF1) from the adrenal glands
    2. Increased levels of growth hormone stimulate increased production of vasopressin from the adrenal glands
    3. Increased levels of growth hormone stimulate increased production of vasopressin from the liver
    4. Increased levels of growth hormone stimulate increased production of insulin like growth factor one (IGF1) from the liver
  37. What do Leydig cells produce?
    1. Testosterone
    2. Semen
    3. Androgen binding globulin
    4. Oestrogen
  38. Which of the following are common symptoms of hypothyroidism?
    1. Weight gain
    2. Hyporeflexia
    3. Hair loss
    4. Oily skin
    5. Excessive hair growth
    6. Weight loss
    7. Dry skin
  39. Which one of the following statements best defines dipsogenic diabetes insipidus?
    1. Dipsogenic diabetes insipidus is caused by a defect or damage to the pituitary gland causing malfunction of the thirst mechanism.
    2. Dipsogenic diabetes insipidus is caused by a defect or damage to the pituitary stalk causing malfunction of the thirst mechanism.
    3. Dipsogenic diabetes insipidus is caused by a defect or damage to the hypothalamus causing malfunction of the thirst mechanism.
    4. Dipsogenic diabetes insipidus is caused by a defect or damage to the pituitary stalk causing malfunction of the hunger mechanism.
  40. Which of the following hormones are produced by the adrenal cortex?
    1. Epinephrine (adrenaline)
    2. Aldosterone
    3. 5-DHEA
    4. Cortisol
    5. Norepinephrine (noradrenaline)

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