Cyclic citrullinated peptide (CCP) antibody testing detects and measures CCP antibodies in the blood. CCP antibodies are produced by the immune system and can accidentally attack healthy tissues.
A blood sample is required for a CCP antibody test. This test is used to diagnose or rule out rheumatoid arthritis and to assess its possible severity. Rheumatoid arthritis is an autoimmune disorder in which the body attacks healthy cells in a person’s joints.
| Also Known as | CCP Antibody, Citrulline Antibody, Anti-citrulline Antibody, Anti-cyclic Citrullinated Peptide, Anti-CCP, ACPA, Cyclic Citrullinated Peptide Antibody |
| Test Purpose | To Diagnosing rheumatoid arthritis To Estimating disease severity |
| Test Preparations | No Special Preparation Required |
| Test Components | Anti CCP |
| Specimen | 2 ML (1 ML Min.) Serum From 1 SST. Ship Refrigerated Or Frozen. |
| Stability Room | 2 Hrs |
| Stability Refrigerated | 48 Hrs |
| Stability Frozen | 1 Week |
| Method | ELISA |
| Download Report | Download Report |
Why to Get Tested:
- To Diagnosing rheumatoid arthritis
- To Estimating disease severity
When to get Tested:
You may need this test if you have symptoms of rheumatoid arthritis. These include:
You may also need this test if other tests couldn’t confirm or rule out a diagnosis of rheumatoid arthritis.
Test Preparation:
No Need any Preparation for this test
Sample Required
2-3 ml Blood in SST or Yellow cap Tube
REJECT DUE TO
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
| Heat-treated specimen | Reject |
Normal Values:
- <20.0 U (negative)
- 20.0-39.9 U (weak positive)
- 40.0-59.9 U (positive)
- > or =60.0 U (strong positive)
Reference values apply to all ages.
Negative Result Mean:
Negative CCP antibodies and negative RF, it means you are less likely to have rheumatoid arthritis. Your provider may need to do more tests to help find out what is causing your symptoms.
Positive Result Mean:
- Positive CCP antibodies and positive RF, it likely means that you have rheumatoid arthritis.
- Positive CCP antibodies and negative RF, it may mean you are in the early stages of rheumatoid arthritis or will develop it in the future.
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