Search Here

Angiotensin-1-Converting Enzyme Test

Angiotensin converting enzyme (ACE) is an enzyme that converts angiotensin I to angiotensin II. Angiotensin II helps increase blood pressure by causing the body’s small blood vessels to constrict or narrow.

Also Known As:  ACEAngiotensin-1-Converting Enzyme, Kinase II, Peptidylpeptide Hydrolase, SACE (Serum Angiotensin Converting Enzyme), Sarcoidosis, Serum Angiotensin Converting Enzyme

ACE Test

email_subscription

Receive all our future posts instantly in your inbox. Enter your email to enroll.

Why to Get Tested:

Most of the time we uses the ACE level test to monitor a disease called sarcoidosis. This condition causes inflammatory cells called granulomas to form in the body, leading to inflammation of the organs. Organs that can be affected by sarcoidosis include:

  • lungs
  • skin
  • eyes
  • lymph nodes
  • liver
  • heart
  • spleen

When to get Tested:

  • When you have granulomas that produce small bumps under the skin.
  • When you have a lingering cough.
  • When you have red watery eyes.
  • When you have symptoms suggestive of sarcoidosis.
  • Regularly when you have active sarcoidosis to monitor its course.

Other symptoms include:

  • night sweats
  • a loss of appetite
  • swollen lymph nodes
  • joint pain
  • dry mouth
  • nosebleeds

Sample Required:

Collection Container/Tube:

  • Preferred: Serum gel
  • Acceptable: Red top
  • Submission Container/Tube: Plastic vial
  • Specimen Volume: 1.5 mL

How to Prepare for the Test

Follow your health care provider’s instructions for not eating or drinking for up to 12 hours before the test. If you are on steroid medicine, ask your provider if you need to stop the medicine before the test, because steroids can decrease ACE levels. DO NOT stop any medicine before talking to your provider.

Reject Due To 

Gross hemolysisReject
Gross lipemiaReject
Gross icterusReject

Specimen Stability Information 

Specimen TypeTemperatureTimeSpecial Container
SerumRefrigerated (preferred)7 days
 Frozen 180 days
 Ambient 24 hours

Normal Values:

Normal Value of ACE : Upto 40 mg/l

High ACE Level Seen in:

  • Cancer of the lymph tissue (Hodgkin disease)
  • Diabetes mellitus
  • Liver swelling and inflammation (hepatitis) due to alcohol use
  • Lung disease such as asthma, cancer, chronic obstructive pulmonary disease, or tuberculosis
  • Kidney disorder called nephrotic syndrome
  • Multiple sclerosis
  • Adrenal glands do not make enough hormones (Addison disease)
  • Stomach ulcer
  • Overactive thyroid (hyperthyroidism)
  • Overactive parathyroid glands (hyperparathyroidism)

Low ACE Level Seen in:

  • Chronic liver disease
  • Chronic kidney failure
  • Eating disorder called anorexia nervosa
  • Steroid therapy (usually prednisone)
  • Therapy for sarcoidosis
  • Underactive thyroid (hypothyroidism)

Related Articles:

  • Aldolase is an enzyme that helps convert glucose (sugar) into energy. It is found throughout […]
  • Ammonia is a nitrogen waste compound that is normally excreted in the urine. An elevated […]
  • Ammonia is a nitrogen waste compound that is normally excreted in the urine. An elevated […]
  • Ammonia is a nitrogen waste compound that is normally excreted in the urine. An elevated […]
  • Ammonia is a nitrogen waste compound that is normally excreted in the urine. An elevated […]
  • Ammonia is a nitrogen waste compound that is normally excreted in the urine. An elevated […]
  • Real-time PCR (quantitative PCR, qPCR) is now a well-established method for the detection, quantification and […]
  • General Purpose media is designed to grow most organisms and do not contain growth inhibitors. […]


Possible References Used


Leave a Reply

Your email address will not be published. Required fields are marked *

Navigate: Home | Categories | About Us | Authors | Contact Us | Submit News Tips | Advertise | Write for Us
Find us on: Facebook | Twitter | Tumblr | YouTube | Reddit | Pinterest | Instagram
More: RSS | Sitemap | Back to: Top
© 2018-2020 Lab Tests Guide