Leukocyte esterase is a screening test used to detect a substance that suggests there are white blood cells in the urine. This may mean you have a urinary tract infection. If this test is positive, the urine should be examined under a microscope for white blood cells and other signs that point to an infection.
A urinalysis is a test of your urine. A urinalysis is used to detect and manage a wide range of disorders, such as urinary tract infections, kidney disease and diabetes.
A urinalysis involves checking the appearance, concentration and content of urine. Abnormal urinalysis results may point to a disease or illness.

Also Known as: Urine Test, Urine Analysis , Urine CE, Urine C/E, UCE, Urinalysis
Test Panel: Physical properties, Chemical Tests, Dipstick Tests, Microscopic Examination
Type of urine samples:
- Random sample:
This is a diluted urine sample and may give an inaccurate interpretation of patient health. But is best to do microscopy to evaluate WBC or RBC. - First Morning sample:
This is the best sample for microscopy and urine analysis. This is the concentrated urine because of urine remained throughout the night in the urinary bladder. This will contains an increased concentration of analytes and cellular elements. Urine must have remained in the bladder for 8 hours is considered as the first-morning sample. - Urine for sugar (Postprandial 2 hours):
Postprandial 2 hours sample collected after 2 hours of high carbohydrate diet. - Midstream clean catch urine:
This sample is needed for the culture and sensitivity of urinary infection. The patient is advised to clean the urethra, then discard the first few mL of urine. Now midstream of the urine is collected in the sterile container. - 24 Hours of a urine sample
- In this case, discard the first urine and note the time.
- Now collect urine in the container for 24 hours and put the last sample in the container.
- Refrigerate the sample.
- This 24 hours samples are needed for measuring urea, creatinine, sodium, potassium, glucose, and catecholamines.
- Suprapubic collection of the urine sample:
This is done in the patients who cannot be catheterized and the sample is needed for culture. This sample is collected by the needle. - Catheter collection of urine:
This is done by patients who are bedridden and can not urinate. - Pediatric urine sample:
In infants, special collection bags are made adherent around the urethra. Then urine is transferred to a container.
Urine Leukocytes
Leukocyte esterase is a screening test used to detect a substance that suggests there are white blood cells in the urine. This may mean you have a urinary tract infection. If this test is positive, the urine should be examined under a microscope for white blood cells and other signs that point to an infection.

Symptoms
Leukocytes in urine don’t necessarily cause symptoms on their own. If you do have leukocytes in your urine, your symptoms will vary depending on the condition that is causing the leukocytes to build up in your urine.
The symptoms of a UTI include:
- a frequent urge to urinate
- a burning sensation when urinating
- cloudy or pink-tinted urine
- strong smelling urine
- pelvic pain, especially in women
If your doctor suspects you have a UTI, they’ll likely ask you to provide a urine sample. They’ll test the urine sample for:
- WBCs
- red blood cells
- bacteria
- other substances
Why get Tested:
- some cancers, such as prostate, bladder, or kidney cancer
- blood diseases such as sickle cell anemia
- some pain relieving medicines
- interstitial cystitis
Normal Range:
Normally Nitrite is absent in the urine
Sample Required:
- The sample is urine.
- The random sample can be taken.
Related Articles:
Possible References Used