Binding of specific cell or tissue structures (usually proteins) by an antibody directed against that protein. This antibody is often raised in a species other than the one from which the specimen is taken. For example, antibodies may be developed in rabbits to a protein present in human tissue. There are several methods for visualizing where these antibodies have bound to the tissue. In the example above, other antibodies directed against rabbit proteins that are […]
Abnormally shaped red blood cells with one or more semicircular portions removed from the cell margin, the cells appearing to have been “bitten” or “bitten”. “Stings” result from the removal of hemoglobin with an altered (denatured) structure by special cells (macrophages) in the spleen. G6PD deficiency is a common disorder that leads to the formation of bite cells, which can be seen in a stained blood smear.